1229582-33-5 URMC-099, 一种口服生物有效的混合谱系激酶3 (MLK3) (IC50=14 NM) 抑制剂

• CAS：1229582-33-5
• 分子式：C27H27N5
• 分子量：421.548

• 中文别名
  3-(1H-吲哚-5-基)-5-[4-[(4-甲基-1-哌嗪基)甲基]苯基]-1H-吡咯并[2,3-B]吡啶; URMC-099抑制剂; 化合物URMC099; 更多
• 英文名称
  URMC-099
• 英文别名
  3-(1H-indol-5-yl)-5-[4-[(4-methylpiperazin-1-yl)methyl]phenyl]-1H-pyrrolo[2,3-b]pyridine; CS-1776; 3-(1H-indol-5-yl)-5-[4-[(4-methyl-1-piperazinyl)methyl]phenyl]-1H-pyrrolo[2,3-b]pyridine; URMC 099; 1H-?Pyrrolo[2,?3-?b]?pyridine, 3-?(1H-?indol-?5-?yl)?-?5-?[4-?[(4-?methyl-?1-?piperazinyl)?methyl]?phenyl]?-; 1H-Pyrrolo[2,3-b]pyridine, 3-(1H-indol-5-yl)-5-[4-[(4-methyl-1-piperazinyl)methyl]phenyl]-; 3-(1H-Indol-5-yl)-5-{4-[(4-methyl-1-piperazinyl)methyl]phenyl}-1H-pyrrolo[2,3-b]pyridine; PEPOSERTIB, MSC2490484A; 3-(1H-indol-5-yl)-5-[4-[(4-methylpiperazin-1-yl)methyl]phenyl]-1H-pyrrolo[2,3-b]pyridine URMC-099; 3-(1H-indol-5-yl)-5-[4-[(4-methylpiperazin-1-yl)methyl]phenyl]-1H-pyrrolo[2,3-b]pyridine URMC-099; RMC099; 更多

• 密度：1.256±0.06 g/cm3(Predicted)
• 折射率：1.711
• PSA：50.95000
• LOGP：3.85